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An increasing number of countries3 are reporting patients suffering from extensively drug-resistant TB (XDR-TB) – which is MDR-TB additionally resistant to at least one fluoroquinolone and a second-line injectable.1
Only 28% of people suffering from XDR-TB globally are successfully treated.1
Otsuka has had a TB medicine discovery programme for over 40 years and has been a recognised leader in TB research through its commitment to the development of new TB compounds as well as the building of a clinical infrastructure within developing countries affected by the disease.
One of the compounds developed by Otsuka has received regulatory approval for treatment of adults with pulmonary MDR-TB as one of first TB medicines in about 50 years.4 Apart from continuing its research and development programme, Otsuka is also engaging in multiple third-party collaborations looking at shorter, more effective and more patient-friendly ways to fight MDR-TB.
1. World Health Organization. Global Tuberculosis Report 2016. World Health Organization, Geneva, 2016.
2. World Health Organization. Tuberculosis Factsheet 104. Reviewed March 2017. Available at: http://www.who.int/mediacentre/factsheets/fs104/en/ (Accessed 19 June 2017).
3. By the end of 2015, XDR-TB had been reported by 117 countries.
4. Gualano G., et al. New Antituberculosis Drugs: From Clinical Trial to Programmatic Use. Infect Dis Rep. 2016; 8(2): 6569.
Information current as of 26-06-2017